FMO3 Malodor / TMAU : list of tests from good Metabolic Unit / Genetics Clinic

last update : Oct22 Tests a TMAU patient (correct disorder name - FMO3 Malodor) should look to get from a Metabolic Unit visit, or from a Geneticist. imho this is a list of tests that Metabolic Units or Geneticists should use for patients referred for suspected 'TMAU' (imho proper disorder name : FMO3 MALODOR (mostly sulfides)).You have a right to ask for these tests. If refused then offer...

Read More

By sysbodyodor

No comments

my (current) opinion on FMO3 MALODOR (imho Fecal Body Odor)

My CURRENT opinion (self-styled expert) on the cause of 'FECAL BODY ODOR' (it's actually worse than that, as it can be fart smells, rotten egg, burnt rubber .... it's sulfide smells from the colon)  It's all to do with FMO3 ENZYME (weakness, overload etc)(my view hasn't changed much, but my opinion is more fixed and precise)Type 1 genetic : SEVERE RARE (the fish smellers)The FISH SMELL is the...

Read More

By sysbodyodor

2 comments

someday : 'fecal body odor' debate in Parliament ?

Someday politicians could be having a debate about 'fecal body odor' 'metabolic body odor' 'systemic body odor' 'TMAU' in their parliament / senate / congress etc. Recently a 'M.E.' debate was held in the UK Parliament. Here is the UK 'request for debate' stage (to show the interest of the MPs of all parties)   Someday they could be talking about (choose your label) : FECAL BODY ODOR METABOLIC...

Read More

By sysbodyodor

campaign, community, fecal body odor, metabolic/systemic malodor

No comments

FMO3 survey to understand patterns in community

I would suggest its better to do the FMO3 DNA test first rather than the Urine test. It's important we see a pattern of FMO3 variants to use as proof and to understand. The FMO3 coding part is a 532 amino acid sequence (3 x 532 nucleotides) Ways to FMO3 DNA test : Full sequencing (hard to access) 23andme (23 of the 532 codons) Geneology dna tests (raw data ... about 25 codons ?) Ethnicities often...

Read More

By sysbodyodor

fecal body odor, fmo3, systemic body odor, systemic malodor syndrome

No comments

Paper : TMAO converts back to TMA by bacteria

New paper : Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Reading Uni UK. About : How some gut bacteria can break down TMAO back to TMA. Full paper : Link Significance to TMAU : Probably not that significant as most gut TMAO in humans would likely be from...

Read More

By sysbodyodor

TMAO Research, tmau

No comments

Comment on the NEW UK TMAU Test (Sheffield)

NEW TEST In early March the 'Sheffield TMAU Test Team' kindly gave a lecture at the UCL Adult Metabolic Unit in London to a group of TMAU patients. Below is an abridged version of the lecture Sheffield NEW TMAU Test lecture slides (hosted on SCH site) The main 'changes' seems to be : Almost...

Read More

By sysbodyodor

campaign, main points, tmau, TMAU stats, tmau test

No comments

North Carolina Uni tests for TMAU

Update : This lab will let a Dr order the test as long as : 1.the patient is DE-IDENTIFIED for the sample. 2. the patient name is not disclosed. i.e. they do not find out the patient details. This would be a special arrangement by your Dr. Insurance will almost definitely not apply. It seems the ZEISEL...

Read More

By sysbodyodor

No comments

Potential 2 year FMO3 Study

A Metabolic Consultant has offered to do a 2 year study on 2 ways to improve FMO3 function. Part 2 (part 1 in the paper). would focus on NONSENSE mutations, which are rare but usually severe. Part 1 would focus on MISSENSE mutations, which will be the vast majority of TMAU1 cases. Speculation suggests...

Read More

By sysbodyodor

announcement, campaign, crowdfunding, fecal body odor, fmo3, FMO3 research, tmau

No comments