It's important we see a pattern of FMO3 variants to use as proof and to understand.
The FMO3 coding part is a 532 amino acid sequence (3 x 532 nucleotides)
Ways to FMO3 DNA test :
Full sequencing (hard to access)
23andme (23 of the 532 codons)
Geneology dna tests (raw data ... about 25 codons ?)
Ethnicities often have 'haplotypes', certain groups of variants.
Below is an 'ad-hoc' quick FMO3 survey.
The results will be made public.
Intention is to look for patterns.
Link for the survey (e.g. to share) https://tinyurl.com/y7kyxzpc
Problems with DNA testing :
If via a Health system lab, they don't give the 532 data, but rather mention variants they think important. They are likely very conservative.
If via 23andme : You need to look in the raw data. Not too hard. E.g. search FMO3.
Why FMO3 ?
FMO3 oxidizes 1,000s of substrates, that are sulfides. amines, or phosphate containing.
It is my current opinion that FMO3 weakness is the cause of most cases of 'fecal body odor'.
Most enzymes have only maybe 1 to 10 substrates to alter.
But the oxidizer group, which includes FMO3, have 1,000s of substrates to alter.
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