News & Views on Systemic Body Odor and Halitosis such as trimethylaminuria TMAU. If you have fecal odors or bowel odors it may be metabolic/systemic

17 April 2014

BORC Podcast of Dr Robin Lachmann conference

BORC (Body Odor Resource Center) has been arranging a number of conference calls with people that may be of interest to people who have trimethylaminuria (TMAU)

The most recent conference call was with Dr Robin Lachmann of the Charles Dent  Metabolic Unit in London. Dr Lachmann has a few years background in seeing TMAU patients.

A podcast of the conference call can be heard on the BORC podcast website
Dr Robin Lachmann conference call with BORC

BORC youtube channel : link

My view on TMAU
Personally I think people with a problem with their FMO3 enzyme may be prone to smelling of various sulfides and amines that are oxidized by FMO3. This would include trimethylamine but it may be a 'small player' in the number of compounds the person smells of. TMAU came about because the professionals at the time were only looking for trimethylamine. There has been no attempts to look for other compounds. However TMAU is a useful lever to rasie awareness of the concept of metabolic malodors, and trimethylamine should also  be a good biomarker of FMO3 function which I suspect is the main enzyme responsible for most cases of metabolic malodor.

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FMO3 DNA testing
Update Aug 17 :
Genos is back with it's EXOME test
link

Note :
Exome/Genome testing may be better option than single gene testing.

See this post : link

Note : Genos Exome Testing.

Exome testing is almost the same price now as single gene testing. Also Genos is consumer friendly, which standard DNA labs are not.

So the blog offer to test solely for FMO3 is almost obsolete, and so no longer offered.


Does Genos fully sequence FMO3 gene ?

At the moment it is not clear, but hoped this will become clear over the next few months

Note : possible 'wild west' way of testing FMO3
Use an ancestry dna site and rummage through the raw data

TMAU Webinar #5 : Preti et al