Metabolomic Profiling for Systemic Body Odor

This post is meant to be thought provoking. Need to discover all volatiles/metabolites that cause systemic body odor. Once discovered, these volatiles will be known as the biomarkers for the diagnostic test, Trimethylaminuria (TMAU) was 'discovered' in 1970 by Denver Dr's. A patient's mother had...

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By sysbodyodor

Body Odor, fecal body odor, metabolic/systemic malodor, metabolic/systemic malodor research, systemic body odor, systemic malodor syndrome

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Paper : firmicutes produce more TMA than bacteroides

New paper : The aim seems to be to see how trimethylamine precursors (choline in foods etc) affect TMA-oxide levels in a group of healthy young men. The conclusion seems to be that those with a higher ratio of Firmicutes / Bacteroide gut bacteria generate more trimethylamine from precursors.  ...

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By sysbodyodor

stool dna, TMAO Research, TMAO-CVD

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FMO3 codon 285 'silent mutation' : N285N

The DNA code for FMO3 is a 1596 nucleotide sequence (532 x 3). This 532 x 3 nucleotide sequence creates a 532 amino acid sequence which creates the FMO3 protein. codon 3-nucleotide code resulting amino acid 283 gta valine 284 ttt phenylalinine 285 ...

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By sysbodyodor

fmo3, FMO3 reference, systemic body odor, systemic malodor syndrome

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P&G TMA-blocker will be stronger than DMB

In a magazine article in April about the gut flora, this statement was made "Hazen says DMB, the olive-oil molecule from his study, is too weak to put into a pill. He’s working on creating stronger inhibitors." So it looks like something stronger than DMB will be used by the Cleveland Clinic for...

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By sysbodyodor

DMB pill, gut dysbiosis, metabolic malodor, metabolic/systemic malodor research, possible future therapy, systemic body odor, TMAO Research

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