The question is does it stop trimethylamine formation ?
This new paper is probably due to all the interest in TMA-oxide and CVD
This is a new one-off paper by Latvian researchers : Feb 2016
Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity.
Link : meldonium TMAO abstract
Quote from paper : Here, we briefly reviewed the pharmacological effects and mechanisms of meldoniumin treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.
Note : I only have access to the abstract, not the full paper
What has this to do with TMAU ?
It looks like meldonium somehow interferes with TMA-oxide formation. I don't know if this means it also blocks trimethylamine formation. If it did, then I guess it would be similar to the hoped the Cleveland Clinic have for the natural compound DMB.
My current opinion :
I guess it's worth checking up further but I'm not overly interested. Partly because I suspect people with 'FMO3 body/breath malodor' probably have issues with many sulfides and amines, not just TMA. Plus with DMB hopefully being available sometime in the future and being OTC, I'm hoping this will do the same job.
wikipedia : meldonium
Quote from paper : Here, we briefly reviewed the pharmacological effects and mechanisms of meldoniumin treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.
Note : I only have access to the abstract, not the full paper
What has this to do with TMAU ?
It looks like meldonium somehow interferes with TMA-oxide formation. I don't know if this means it also blocks trimethylamine formation. If it did, then I guess it would be similar to the hoped the Cleveland Clinic have for the natural compound DMB.
My current opinion :
I guess it's worth checking up further but I'm not overly interested. Partly because I suspect people with 'FMO3 body/breath malodor' probably have issues with many sulfides and amines, not just TMA. Plus with DMB hopefully being available sometime in the future and being OTC, I'm hoping this will do the same job.
wikipedia : meldonium
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