News & Views on Systemic Body Odor and Halitosis such as trimethylaminuria TMAU. If you have fecal odors or bowel odors it may be metabolic/systemic

6 April 2014

Ellie raises TMAU awareness in a UK national paper

Ellie James has done much to raise awareness of trimethylaminuria (TMAU). She has done previous media items, and now has kindly and bravely volunteered for an article in the UK national newspaper, the Daily Mirror.

The article can be read here : Ellie talks about TMAU in The Daily Mirror

My view on TMAU
Personally I think TMAU may only explain 'fish malodor', as trimethylamine is said to smell of rotting fish. However the enzyme that oxidizes trimethylamine (flavin mono-oxygenase 3 (FMO3)) oxidizes 1,000's of sulfides and amines in the body, so I think 'fecal-gas-unpleasant malodors' circulating systemically in humans may be due to sulfides and amines most likely to use FMO3 as their route of oxidising. And so a  FMO3 enzyme problem (either genetic or overload or both) and raising awareness of TMAU will still be likely to benefit what may be the real disorder people with many unpleasant metabolic malodors may have, FMO3 substrate malodors.

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Update Aug 17 :
Genos is back with it's EXOME test
link

Note :
Exome/Genome testing may be better option than single gene testing.

See this post : link

Note : Genos Exome Testing.

Exome testing is almost the same price now as single gene testing. Also Genos is consumer friendly, which standard DNA labs are not.

So the blog offer to test solely for FMO3 is almost obsolete, and so no longer offered.


Does Genos fully sequence FMO3 gene ?

At the moment it is not clear, but hoped this will become clear over the next few months

Note : possible 'wild west' way of testing FMO3
Use an ancestry dna site and rummage through the raw data

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