News & Views on Systemic Body Odor and Halitosis such as trimethylaminuria TMAU. If you have fecal odors or bowel odors it may be metabolic/systemic

6 October 2016

FMO's explained in youtube video

There looks to be very little about the flavin mono oxygenase group of enzymes on the internet so far.
Any video is worth a look.
This video seems to be by a PhD who specializes in 'allied health' (e.g. nurses) and is explaining FMO's mostly from a toxicology aspect.



Comments on the video :
Mentions interest in FMO's only from around 1960's - 1990's.
FMO's are thought of as 'poor relation' to CYP450 enzyme group in toxicology.
6 FMO isoforms in humans known. Currently FMO3 regarded as the 'main' FMO.
He mentions 'thiols' in the video, which may be a group that explain most 'FMO malodors' (maybe not).

What has FMO3 to do with systemic body odor ?
My own (current) view is that FMO3 metabolites may cause most of the malodors in 'systemic body odor', due to the FMO3 enzyme being sub-par. What I mean is, the sub-par FMO3 function causes the odors. Perhaps there are other forms of systemic body odor but this is my own view of what may be the most common type.  

wikipedia : flavin mono oxygenases


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FMO3 DNA testing
Update Aug 17 :
Genos is back with it's EXOME test
link

Note :
Exome/Genome testing may be better option than single gene testing.

See this post : link

Note : Genos Exome Testing.

Exome testing is almost the same price now as single gene testing. Also Genos is consumer friendly, which standard DNA labs are not.

So the blog offer to test solely for FMO3 is almost obsolete, and so no longer offered.


Does Genos fully sequence FMO3 gene ?

At the moment it is not clear, but hoped this will become clear over the next few months

Note : possible 'wild west' way of testing FMO3
Use an ancestry dna site and rummage through the raw data

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