At the prototype stage.
Isense Systems own the IP rights but unlikely to make a device.
You can contact them to encourage them.
Protoype created by Suslick lab at University of Illinois.
Encouraged by me contacting him a few years ago.
Uses disposable color paper to identify TMA levels.
Not an ideal sensor solution but only one mentioned so far.
Abstract of paper : Rapid Quantification of Trimethylamine
Abstract
Sensitive detection of trimethylamine both in aqueous and gaseous phases has been accomplished using an inexpensive colorimetric sensor array. Distinctive color change patterns provide facile discrimination over a wide range of concentrations for trimethylamine with >99% accuracy of classification. Calculated limits of detection are well below the diagnostically significant concentration for trimethylaminuria (fish malodor syndrome). The sensor array shows good reversibility after multiple uses and is able to cleanly discriminate trimethylamine from similar amine odorants. Portable sensing of trimethylamine vapors at ppb concentrations is described using a cell phone camera or a hand-held optoelectronic nose. Application of the sensor array in detecting mouth and skin odor as a potential tool for portable diagnosis of trimethylaminuria is also illustrated.
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| not a tma sensor |
I enquired to the Suslick lab about this a few years ago, and now they have created a prototype device (about size of cigar) that connects to a cellphone. It uses disposable colorimetric paper.
Ideal trimethylamine sensor :
connects to a phone (maybe bluetooth).
small device.
no need for accessories.
works like a alcohol breath sensor.
The colorimetric device is not ideal but perhaps worth following up as it's the only known TMA sensor at the moment. If you feel it might help it might be worth contacting Isensesystems.com to register an interest in a trimethylamine sensor. It would seem unlikely they will go ahead but hearing of interest may encourage them.
email isensesystems.com
sub-par FMO3 needs :
cheap and accessible TMAU urine and DNA test
TMA sensor
Gene Therapy cure and other treatments (e.g. DMB)
My own view :cheap and accessible TMAU urine and DNA test
TMA sensor
Gene Therapy cure and other treatments (e.g. DMB)
As mentioned, it doesn't seem an ideal solution, but is the only proposed TMA sensor I have heard of yet. While TMA may be a 'signature' volatile for those with sub-par FMO3 enzyme function, my own view is that those with sub-par FMO3 are likely to smell of many sulfides and amines. Nevertheless, detecting TMA is a start/
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