New paper on the FMO group of enzymes by Uni of Washington researchers. They look at FMO's in nematodes, and the conclusion in this paper is that "FMOs are conserved in eukaryotes and induced by multiple life span-extending interventions in mice, which suggests that these enzymes may play a critical role in promoting health and longevity across phyla."
Link to abstract (pubmed)
My own view on the abstract :
I only have access to the abstract. To me it seems to say that the FMO group of enzymes (FMO3 the most abundant in humans) may play some sort of positive health and longevity role in all animals. I presume this must be taken as a 1st paper on the connection and not a mainstream consensus.
Connection with Fecal Body Odor / TMAU / systemic body odor :
It's my own view that FMO3 may be the main suspect in human 'metabolic malodor' syndrome. So any resaearch on FMO enzymes and FMO3 in particular I think may be of use to those with metabolic malodor. FMO's tend to oxidize many common small sulfides and amines, so I suspect people with 'FMO3 metabolic malodor' will smell of these sulfides and amines.
What will happen because of this paper ?
I can see 3 possible outcomes :
1. nothing will happen
2. They may keep researching and do a few more papers that don't have much impact.
3. The research world is bowled over by the paper and they all throw money and research into it (to various degrees). Very unlikely I think.
Things to remember about the paper
Done in nematodes, but they say could apply in humans
Might be a one-off paper with little impact (hopefully not)
Researchers have no history of an interest in TMAU etc.
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