For the TMAU urine test, there are 2 main metabolites tested
trimethylamine (TMA)
and trimethylamine-n-oxide (TMAO)
Basically, if the TMA is over a set limit, you are deemed to have TMAU
If the TMA/TMAO ratio is over a set limit, you are deemed to have primary TMAU1
This is often expressed as the TMAO % (equation TMA + TMAO/TMAO)
That's it. Unfortunately, there is no agreement between the labs that test to the set limits (each have their own reference range). To make it more confusing, it seems many of the labs have not set a limit for TMA, and only go by the ratio (therefore, refuse to label anyone as secondary TMAU). If you have the figures you can work out yourself roughly if you would be TMAU2. If you only have the ratio or %, you cannot.
Conversely, some labs only give the TMA level as a result, and do not measure TMAO. This means you do not know how much of the TMA you oxidized, and you do not know if you are TMAU1 or TMAU2
There are other problems with the testing procedures, such as some saying no load is needed, and others saying choline, while others say fish. It is a bit of a minefield.
My own personal preferred option would be to take a load of TMA (probably around 600mg) and see what the TMA and TMAO levels are. This is a straight test of how well your FMO3 enzyme copes with a fixed load of TMA. From there I would then maybe want to find out if bacterial growth is a big factor, by taking a choline load. Overall though, I am not majorly concerned at the moment about bacterial overgrowth, but rather how well the enzyme functions.
Creatinine is also measured in TMAU urine test. This is basically merely as something to reference the TMA and TMAO levels against.
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