News & Views on Systemic Body Odor and Halitosis such as trimethylaminuria TMAU. If you have fecal odors or bowel odors it may be metabolic/systemic

21 May 2016

Popular Science article on TMAO / CVD theory

A good article for the public on the timeline of the trimethylamine-oxide and cardiovascular disease connection theory, posted on the website Popular Science.

The first paper on the TMAO - CVD theory was published in 2011.
The notion being that TMAO may be a major factor in causing CVD.
Published by Dr Stan Hazen et al at the Cleveland Clinic.
Research still ongoing, including finding that DMB inhibits TMA production in the gut.
This would be very good for those with Trimethylaminuria.
A deal is signed with Proctor & Gamble to market a DMB product which hopefully will also be beneficial for TMAU.

Link : Popular Science article on TMAO  

The team went as far as to define particular bacterial genera responsible for the condition.
.....
The authors themselves suggest there may be a route forward by trying to target the TMAO pathway in microbes.


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Update Aug 17 :
Genos is back with it's EXOME test
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Note :
Exome/Genome testing may be better option than single gene testing.

See this post : link

Note : Genos Exome Testing.

Exome testing is almost the same price now as single gene testing. Also Genos is consumer friendly, which standard DNA labs are not.

So the blog offer to test solely for FMO3 is almost obsolete, and so no longer offered.


Does Genos fully sequence FMO3 gene ?

At the moment it is not clear, but hoped this will become clear over the next few months

Note : possible 'wild west' way of testing FMO3
Use an ancestry dna site and rummage through the raw data

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